Benfotiamine, a lipid-soluble derivative of vitamin B1 (thiamine), has several clinical applications, primarily due to its ability to increase intracellular thiamine levels and reduce advanced glycation end products (AGEs) and oxidative stress. Here’s a detailed overview: 1. Diabetic Complications Benfotiamine…
Benfotiamine (S-benzoylthiamine-O-monophosphate) is a synthetic, lipid-soluble thiamine derivative. Chemical structure of Benfotiamine Formula: C₁₉H₂₃N₄O₆PS Exact mass: ~470.45 g/mol IUPAC: S-benzoylthiamine O-monophosphate The benzoyl group is the key — this blocks water-loving ionic sites → this is why Benfotiamine is fat-soluble (standard thiamine is…
Benfotiamine (rINN, or S-benzoylthiamine O-monophosphate) is a synthetic, fat-soluble, S-acyl derivative of thiamine (vitamin B1) that is approved in some countries as a medication or dietary supplement to treat diabetic sensorimotor polyneuropathy. Benfotiamine was developed in the late 1950s in…
Benfotiamine is a synthetic, fat-soluble form of Vitamin B1 (Thiamine) that is used mainly to support nerves + lower “AGEs” (advanced glycation end products). This is general information only — not personal medical advice. If you’re on medications (especially diabetes…
Benfotiamine is basically a synthetic fat-soluble derivative of vitamin B1 (thiamine). To be more precise: Parent / basic ingredient: → Thiamine (Vitamin B1) Benfotiamine is chemically: So the core backbone is thiamine, but modified with a benzoate (benzoyl) group and…
Benfotiamine = a synthetic lipid-soluble derivative of thiamine (vitamin B1). Different from regular thiamine because it gets into cells more efficiently and more into the “transketolase pathway” → less harmful AGEs. Main evidence-based application zones Application Why it’s relevant Human…
Benfotiamine supplementation improves cognitive function, reduces oxidative stress, and enhances nerve health, positioning it as a potential therapy for neurodegenerative diseases. Here’s a clear comparison between Benfotiamine and Thiamine (Vitamin B1), highlighting their differences, similarities, and uses: Feature Thiamine (Vitamin B1)…
What Benfotiamine is (quick) Benfotiamine = a fat-soluble derivative of vitamin B1 (thiamine). Because it is fat-soluble, it enters cells more efficiently than regular thiamine. The main researched benefits 1) ↓ AGE formation (Advanced Glycation End-products) This is its strongest…
Benfotiamine is a synthetic, fat-soluble derivative of vitamin B1 (thiamine). Because it’s fat-soluble, the body absorbs it much more efficiently than the common water-soluble thiamine salts (like thiamine hydrochloride). So you can get much higher thiamine levels into tissues using…