3-O-Ethyl Ascorbic Acid Powder Supplier | Manufacturing & Production

3-O-Ethyl Ascorbic Acid Powder Supplier | Manufacturing & Production


$120.00/kilogram. order : 1 kilogram

Lead time:

Quantity (kilograms)1 – 100> 100
Lead time (days)5To be negotiated
Essential details
CAS No.:86404-04-8
MF: C8H12O6
EINECS No.:/Place of Origin:
Shaanxi, China
Appearance: White powder
Usage: Cosmetic Raw Materials
Product name: Ethyl Ascorbic Acid
Test Method: HPLC
Grade: Cosmetic Grade
Certification: ISO/HALAL/KOSHER
MOQ: Any order quantity is welcome
Sample: Freely Offered
COA/MSDS/TDS: Available
Application: Cosmetic ingredients

Packaging & deliveryPackaging Details1kg/Aluminum foil bag with one plastic bag inside.
10kg/Carton Box with two plastic bags inside.
25kg/Paper-drum with two plastic bags inside.
Or as per the customer’s requirement.PortShanghai port Ningbo port Qingdao port

3-O-Ethyl Ascorbic Acid Powder Supplier | Manufacturing & Production

Introduction to 3-O-Ethyl Ascorbic Acid

3-O-Ethyl Ascorbic Acid is a stable, water-soluble, and oil-soluble derivative of pure Vitamin C (ascorbic acid)[1]. It offers all the major benefits of Vitamin C, such as brightening skin tone, reducing wrinkles, significantly firming, fading excessive pigmentation, restoring a more even skin tone, and counteracting various environmental damage factors[1].

How 3-O-Ethyl Ascorbic Acid Works

As an improved and more stable version of pure Vitamin C, 3-O-Ethyl Ascorbic Acid must be converted to Vitamin C within the skin through a sodium-dependent protein[2]. This process within the skin’s surface layer helps ensure its benefits to the skin. Due to the slower conversion process, 3-O-Ethyl Ascorbic Acid is considered a more easily accepted form of Vitamin C[2]. However, like pure Vitamin C, the ethyl form requires an acidic pH range (4-5.5) for optimal stability[2].

Benefits and Usage in Skincare

The typical dosage of 3-O-Ethyl Ascorbic Acid in skincare ranges from 0.5-5%[3]. Due to its stability, less is needed compared to pure Vitamin C. Depending on the desired benefits, levels above 5% can also be used. Up to 30% has been proven to be non-irritating to human skin samples[3]. This highly stable and promising form of Vitamin C is a skincare superstar, offering antioxidant, collagen-promoting, and skin-brightening properties[3].

3-O-Ethyl Ascorbic Acid Powder Supplier | Manufacturing & Production


In summary, 3-O-Ethyl Ascorbic Acid is a highly stable and effective form of Vitamin C that offers numerous benefits for skin care, including anti-aging, skin brightening, and collagen-boosting effects[1]. Its improved stability and compatibility with various skin types make it an attractive alternative to pure Vitamin C in skincare formulations[2].

what are the benefits of using 3-o ethyl ascorbic acid in skincare?

The benefits of using 3-O-Ethyl Ascorbic Acid in skincare include its potent antioxidant properties, which help neutralize oxidative stress caused by solar radiation (UVB), pollution, and smoking1. It also protects the skin from solar damage or photoaging by neutralizing inflammatory cytokines, such as IL-61. Additionally, 3-O-Ethyl Ascorbic Acid has a slow-release mechanism, ensuring minimal toxic effects or potential skin irritation. This skincare ingredient also has significant anti-aging effects, as it boosts collagen biosynthesis and decreases its degradation, resulting in younger-looking skin with increased firmness and elasticity1. Furthermore, it brightens dull skin, evens skin tone, fades dark spots, and enhances the effectiveness of sunscreens2. Its stability and compatibility with various skin types make it an attractive alternative to pure Vitamin C in skincare formulations3.

how does 3-O-ethyl-L-ascorbic acid help with hyperpigmentation

3-O-Ethyl-L-Ascorbic Acid helps with hyperpigmentation by inhibiting the melanin-biosynthesis pathway in the skin

1. As a derivative of Vitamin C, it works as an antioxidant that neutralizes free radicals, which can contribute to hyperpigmentation

2. When applied topically, 3-O-Ethyl-L-Ascorbic Acid reduces melanin production by inhibiting tyrosinase-related proteins, leading to a more even skin tone and fading of dark spots

3. Additionally, it has been shown to enhance skin tone by reducing melanin through the inhibition of tyrosinase and TRP-2

3. As a stable, water- and oil-soluble derivative of pure Vitamin C, it can be easily absorbed by the skin, ensuring optimal benefits in fading hyperpigmentation and restoring a more even skin tone

3-O Ethyl Ascorbic Acid references

  • Free Radical Biology and Medicine, September 2021, pages 151–169
  • Life, May 2021, pages 1–13
  • International Journal of Pharmaceutics, December 2019, pages 1–9
  • Journal of Cosmetic Science, July-August 2018, pages 233–243
  • AAPS PharmSciTech, June 2016, pages 767–777
  • Fasano et al., 2011W.J. Fasano, W.F. ten Berge, M.I. Banton, M. Heneweer, N.P. Moore
    Dermal penetration of propylene glycols: measured absorption across human abdominal skin in vitro and comparison with a QSAR model
    Toxicol. In Vitro, 25 (2011), pp. 1664-1670

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels, and availability vary by country and region.