What’s ferulic acid?
The chemical name of Ferulic Acid is 4-hydroxy-3-methoxycinnamic acid, which is one of the derivatives of cinnamic acid (also known as cinnamic acid, 3-phenyl-2-acrylic acid, molecular structure). Ferulic acid (sodium ferulate) has anti-platelet aggregation, inhibits platelet serotonin release, inhibits platelet thromboxane a2 (txa2) production, enhances prostaglandin activity, analgesia, and relieves vasospasm. It is the basic raw material for the production of medicines for the treatment of cardiovascular and cerebrovascular diseases and leukopenia. Such as Xinxuekang, Limai Capsule, Mrs. Oral Liquid, etc., it can also play a role in bodybuilding and skin protection in the human body.
How ferulic acid is made?
There are three methods of making ferulic acid.
- Extraction from plant.
Ferulic acid can be obtained from plants in three ways: one is obtained from the combination of ferulic acid and some small molecules, the other is obtained from plant cell walls, and the third is obtained through tissue culture. Ferulic acid in plants is mostly cross-linked with polysaccharides and lignin through ester bonds or self-esterified or etherified to form di-ferulic acid. Generally, the ester bond is broken by alkali method and enzymatic method to release ferulic acid, and then a suitable solvent is used. to extract.
2. Chemical synthesis
The chemical synthesis method of ferulic acid uses vanillin as the basic raw material, and the main organic reactions used are Wittig-Horner reaction and Kneoevenagel reaction
3. Separation and purification method
At present, there are not many methods for purifying ferulic acid. There are mainly solvent extraction and adsorption.
Xi’an Lyphar Biotech Co.,Ltd can supply both natural ferulic acid and synthesis ferulic acid 98%. Customers can indicate their request.
How can ferulic acid work for you?
Normally ferulic acid is an ingredient in many popular skin care products like serums and creams. It’s often paired with vitamins C and E. And also ferulic acid is together with vitamin B 、niacinamide and retinol to keep skin looking smooth.
This ingredient seems safe for most skin types, but except sensitive skin. Do remember to test on hand or neck before you using on face.
How to dissolve ferulic acid powder?
Ferulic acid melting point is 174℃, soluble in hot water, ethanol and ethyl acetate, slightly soluble in ether, insoluble in benzene and petroleum ether. You can choose proper solvent for your ingredients.
Is ferulic acid qualified?
Usually we use high performance liquid chromatography to make test on ferulic acid. The content of ferulic acid was determined by high performance liquid chromatography. The method is simple and rapid, the result is accurate and the precision is high. It is introduced in the literature that the mobile phase mostly adopts acidic system, mainly including methanol-water-phosphoric acid system, methanol-water-glacial acetic acid system, methanol-acetonitrile-water-glacial acetic acid system, etc. The amount of methanol can be adjusted appropriately in the experiment. The content of ferulic acid in compound ginkgo oral liquid was determined by HPLC. The mobile phase was methanol: 1% glacial acetic acid (45:55), the detection wavelength was 320 nm, the flow rate was 1.0 ml/min, and the column temperature was 25 °C. The oxygen intake of ferulic acid has a good linear relationship in the range of 0.176-0.88ug.
Where you can purchase ferulic acid powder?
You can visit Xi’an Lyphar Biotech Co.,Ltd website biolyphar.com and send inquiry to us. We have both natural and synethsis ferulic acid. Except ferulic acid, we can also provide other cosmetic ingredient like we mentioned vitamin C, vitamin B3 and Retinol. Welcome to contact.