Bifida Ferment Lysate depends on several factors, including its formulation, storage conditions, and exposure to environmental stressors. Here’s a detailed overview:
1. Chemical and Biological Stability
Nature: Bifida Ferment Lysate is a probiotic-derived lysate, containing proteins, peptides, nucleic acids, and metabolites from Bifidobacterium fermentation.
pH Sensitivity: It is generally stable in slightly acidic to neutral pH (pH 4–7), which aligns with most cosmetic formulations. Extreme pH (strongly acidic or alkaline) can degrade proteins and reduce efficacy.
Temperature Sensitivity:
- High temperatures (>40°C) can denature proteins and reduce biological activity.
- Refrigeration (2–8°C) improves shelf life and maintains potency.
- Room temperature storage is acceptable for short periods but may shorten functional activity over time.
Oxidation: Oxidative stress can degrade certain metabolites and peptides. Antioxidants in the formulation may help stabilize it.
2. Formulation Considerations
Water Content: High water content can make it prone to microbial contamination; preservatives are typically needed.
Encapsulation / Lyophilization: Freeze-dried or encapsulated forms are more stable for long-term storage.
Compatibility: Avoid strong acids, bases, or oxidizing agents in the same formulation, as these can reduce stability.
3. Packaging and Storage
Light Exposure: Sensitive to UV light; opaque or amber containers help protect it.
Air Exposure: Minimize air contact; use airtight containers to prevent oxidation and contamination.
Shelf Life:
- Liquid form with preservatives: ~12–24 months at room temperature if protected from light.
- Lyophilized form: Often 2–3 years when stored properly.
4. Functional Stability
Even if visually stable, some bioactive components (like peptides or metabolites that affect skin barrier function) may degrade over time. This can reduce its skin-soothing, anti-inflammatory, or barrier-strengthening effects.
Summary:
Bifida Ferment Lysate is moderately stable under controlled conditions. To maximize stability:
- Store in cool, dark conditions.
- Keep pH neutral in formulations.
- Protect from oxidation and high heat.
- Prefer lyophilized or encapsulated forms for longer shelf life.
If you want, I can make a table showing stability under different temperatures, pH levels, and formulations, which makes it easier to visualize for product development. Do you want me to do that?