Dimethylmethoxy Chromanol is a synthetic chromanol derivative widely used in cosmetics and personal care products for its strong antioxidant and skin-protective properties. It is structurally related to chromanols, a class of compounds known for neutralizing free radicals.
1. Chemical Identity
INCI name: Dimethylmethoxy Chromanol
Chemical class: Chromanol derivative (phenolic antioxidant)
Molecular characteristics:
- Contains a chromanol ring structure
- Substituted with methyl and methoxy groups, enhancing stability and lipophilicity
2. Primary Function
Antioxidant: Scavenges reactive oxygen species (ROS)
Anti-aging support: Helps protect skin from oxidative stress caused by UV radiation and environmental pollution
Formula stabilizer: Protects oils, fragrances, and active ingredients from oxidation

3. Physical Properties
Appearance: White to off-white crystalline powder
Odor: Odorless or nearly odorless
Solubility:
- Oil-soluble
- Poorly soluble in water
Stability:
- High thermal stability
- Resistant to oxidation compared with traditional antioxidants (e.g., vitamin E)
4. Typical Applications
Skin care creams and lotions
Serums and anti-aging formulations
Sunscreens and after-sun products
Hair care products
Makeup products (foundations, lipsticks)
5. Usage Level (Typical)
Commonly used at 0.1–1.0% in cosmetic formulations
Effective at low concentrations due to strong antioxidant capacity
6. Safety & Regulatory Status
Considered safe for cosmetic use when used within recommended concentrations
Not classified as a preservative, but often used to support preservative systems
Suitable for leave-on and rinse-off products

7. Key Advantages
Long-lasting antioxidant activity
Better stability than tocopherols
Does not easily discolor formulations
Compatible with a wide range of cosmetic ingredients
