Calcium Hopantenate Hemihydrate is a derivative of hopantenic acid, which is a compound that has been studied for its potential neuroprotective and cognitive-enhancing properties. It is most commonly used as a supplement to improve cognitive function and memory, although its use is not as widespread or well-known as other substances in this category.
Therapeutic Uses:
| Condition | Benefit / Mechanism |
| Cognitive disorders | Improves memory, attention, and learning ability. May support recovery from brain injuries. |
| ADHD / Hyperactivity in children | Mild calming effect, improves attention and behavior. |
| Developmental delay in children | Promotes cognitive and speech development. |
| Epilepsy (as adjunct) | May reduce seizure frequency and improve brain metabolism. |
| Neurotic disorders / Anxiety | Mild anxiolytic effect. Reduces irritability and emotional instability. |
| Encephalopathies (brain dysfunction) | Improves brain metabolism and energy processes. |
| Fatigue and asthenic syndromes | Increases mental and physical endurance. |
| Parkinson’s disease (adjunct) | May improve motor symptoms when combined with other treatments. |
Mechanism of Action:
- Enhances GABAergic activity → calming effect on the nervous system.
- Participates in metabolic processes in nerve cells.
- Promotes brain cell resistance to hypoxia (low oxygen) and toxins.
- Improves glucose metabolism in the brain.
Forms & Dosage:
- Typically available in tablet or syrup form.
- Dosage depends on age, condition, and doctor’s recommendation.
- Often used in pediatric neurology.
Side Effects (rare):
- Allergic reactions (rash, nasal congestion).
- Sleep disturbances (mainly if taken late in the day).
- Irritability (with overdose).