Basic information of 5-Amino-1MQ Iodide

5-Amino-1MQ Iiodide (also known as 5-Amino-1-methylquinolinium Iodide) is a chemical compound that belongs to a class of organic iodides. It is often studied in the context of its biological and pharmacological activities.

Structure and Composition:

  • Chemical Formula: C9H11N2I
  • Molecular Weight: Around 276.1 g/mol
  • Appearance: It is usually found as a crystalline solid.
  • IUPAC Name: 5-Amino-1-methylquinolinium Iodide
  • CAS Number: 6904-56-7
  • Solubility: It is soluble in water and organic solvents like ethanol, which is typical for many iodides.
Basic information of 5-Amino-1MQ Iodide-Xi'an Lyphar Biotech Co., Ltd

Properties of 5-Amino-1MQ Iodide:

  • Appearance: It is typically a solid, often appearing as a pale or off-white powder.
  • Solubility: The compound is soluble in organic solvents like DMSO (dimethyl sulfoxide) but may have limited solubility in water.
  • Stability: Generally stable under standard laboratory conditions but should be stored in a cool, dry place away from light.

Uses 5-Amino-1MQ Iodide:

  • Research: 5-Amino-1MQ Iodide is used in the study of cellular processes and signaling pathways. It acts as an inhibitor of the enzyme NNMT (Nicotinamide N-Methyltransferase), which is involved in the regulation of cellular metabolism and functions like energy balance and inflammation.
  • Potential Therapeutic Role: Due to its ability to inhibit NNMT, it has been explored for potential use in treating diseases related to metabolism, obesity, and even cancer.

Mechanism of Action:

5-Amino-1MQ Iodide works by inhibiting the NNMT enzyme. NNMT catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide (NAM), converting it into 1-methyl-nicotinamide. This pathway has been implicated in various metabolic and inflammatory diseases, so blocking NNMT could influence metabolic processes like fat storage, insulin resistance, and overall energy homeostasis.

Basic information of 5-Amino-1MQ Iodide-Xi'an Lyphar Biotech Co., Ltd

Caution:

  • Toxicity: Its safety profile and toxicity in humans are still under investigation, so it should be handled with care, particularly in laboratory settings.
  • Regulation: Not generally used in clinical settings but remains under research for its potential therapeutic applications.

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