Calcium Hopantenate Hemihydrate (C8H15CaNO4·0.5H2O) is a calcium salt of hopantenic acid, often used as a supplement or pharmaceutical compound. It is a derivative of pantothenic acid (vitamin B5) and is primarily known for its potential neuroprotective properties. Here are some key details about it:
Basic Information of Calcium Hopantenate Hemihydrate:
- Chemical Formula: C8H15CaNO4·0.5H2O
- Molecular Weight: Around 243.3 g/mol
- Appearance: White to off-white crystalline powder or solid.
- Solubility: It is soluble in water, which helps in its bioavailability and absorption in the body.

Uses of Calcium Hopantenate Hemihydrate:
- Pharmacological Applications: It is used in the treatment of certain neurological conditions and to promote cognitive function. It is sometimes used as a nootropic.
- Neuroprotective Effects: It may help to improve brain function, protect neurons, and support the central nervous system.
- Supplementation: It has been explored for use as a supplement for its potential to improve memory, learning, and mental clarity.
Mechanism of Action:
- Calcium hopantenate is believed to influence the acetylcholine system, which plays a crucial role in learning, memory, and other cognitive functions. It might also have an impact on the synthesis of neurotransmitters.
Safety and Side Effects:
- It is generally considered safe when used as directed. However, side effects may include mild gastrointestinal discomfort, and long-term use should be monitored by a healthcare professional.

Notes:
- It is often found in pharmaceutical formulations aimed at improving cognitive performance or as a part of complex supplements.
- As it is a form of pantothenic acid, it may also have some benefits in skin health and metabolic function.
If you’re considering using it or researching it for a specific purpose, it’s always a good idea to consult with a healthcare provider for professional advice.
