Bifida Ferment Lysate (BFL) is a probiotic-derived ingredient commonly used in skincare for its skin barrier repair, soothing, and anti-aging properties. Its formulation versatility depends on its stability, solubility, and compatibility with other ingredients. Here’s a detailed breakdown of suitable dosage forms:
1. Creams and Lotions
- Form: Oil-in-water (O/W) emulsions or water-based creams.
- Reason: Bifida Ferment Lysate is water-soluble and blends well in the aqueous phase.
- Benefits: Provides moisturizing, soothing, and skin barrier support.
- Typical usage: 2–5% (depending on formulation).
2. Serums and Essences
- Form: Water-based or hydroalcoholic solutions.
- Reason: Bifida Ferment Lysate is stable in aqueous solutions and can be incorporated without emulsifiers.
- Benefits: Rapid absorption, good for sensitive or compromised skin.
- Typical usage: 2–3% for effective barrier repair and anti-inflammatory effects.
3. Toners and Mists
- Form: Water-based sprays or hydrosols.
- Reason: Fully water-soluble; can be used as a refreshing, pre-treatment layer.
- Benefits: Hydration and strengthening of the skin barrier.
- Typical usage: 1–3%.
4. Masks
- Form: Sheet masks (with Bifida Ferment Lysate in serum/essence), cream masks, or gel masks.
- Reason: Bifida Ferment Lysate is hydrating and soothing effects are enhanced in occlusive applications.
- Benefits: Calming, repairing, and improving skin texture.
- Typical usage: 2–5% in the mask solution.
5. Gel-based products
- Form: Hydrogels, eye gels, or post-procedure gels.
- Reason: Compatible with aqueous gel systems.
- Benefits: Soothing, cooling, and barrier-supporting for sensitive or irritated skin.
- Typical usage: 1–3%.
Forms to Avoid
- High heat processes: Bifida Ferment Lysate is sensitive to high temperatures (>40–45°C), so avoid adding it during hot emulsification; add in the cool-down phase.
- Strong acids or bases: Extreme pH (<4 or >8) may destabilize BFL.
- High alcohol content: Can reduce efficacy, so avoid in tonics above ~20% ethanol.
Summary:
Bifida Ferment Lysate is best suited for water-based skincare forms: creams, lotions, serums, toners, masks, and gels. It’s added in the cool-down phase to preserve activity, typically at 1–5% concentration.
If you want, I can make a table listing each dosage form with optimal Bifida Ferment Lysate concentration, formulation phase, and benefits—this is super handy for formulators. Do you want me to do that?