Effectiveness, side effects and special precautions of Natamycin

Natamycin is an antifungal medication that is used primarily to treat fungal infections, particularly those involving the eyes or certain types of food. Here’s an overview of its effectiveness, potential side effects, and special precautions:


1.Ocular Use: Natamycin is commonly used in ophthalmology to treat fungal eye infections, such as fungal keratitis (a serious eye infection affecting the cornea). It is considered effective in combating fungal pathogens responsible for these infections.

2.Food Preservation: Natamycin is approved as a food preservative (E235) by various regulatory agencies, including the FDA in the United States. It is used to prevent the growth of molds and yeasts in dairy products like cheese and yogurt. It is effective at inhibiting the growth of these microorganisms, thereby extending the shelf life of the products.

Effectiveness, side effects and special precautions of Natamycin-Xi'an Lyphar Biotech Co., Ltd

Side Effects:

1.Ocular Use: When used in the eye, natamycin is generally considered safe, with minimal systemic absorption. However, some individuals may experience mild and transient side effects, including:

  • Eye irritation
  • Burning sensation
  • Stinging
  • Redness
  • Blurred vision

2.Food Use: Natamycin is generally recognized as safe (GRAS) when used in food products. It has a low potential for toxicity and allergenicity. Consumers are unlikely to experience any adverse effects from consuming foods treated with natamycin.

Special Precautions:

1.Allergies: Individuals with known allergies or hypersensitivity to natamycin should avoid products containing this compound. Allergic reactions can include skin rash, itching, swelling, or difficulty breathing.

2.Ocular Use: Natamycin eye drops or ointments should be used only as prescribed by a healthcare professional. It is essential to complete the full course of treatment, even if symptoms improve, to ensure the complete eradication of the fungal infection.

3.Contact Lenses: If you wear contact lenses, it’s important to remove them before using natamycin eye drops and wait at least 15 minutes before reinserting them. Consult your eye doctor for specific instructions.

4.Pregnancy and Breastfeeding: There is limited data on the safety of natamycin use during pregnancy and breastfeeding. Consult with a healthcare provider before using this medication if you are pregnant or breastfeeding.

5.Drug Interactions: Natamycin is not known to interact significantly with other medications. However, it’s always a good practice to inform your healthcare provider about all the medications and supplements you are taking to avoid potential interactions.

Overall, natamycin is considered effective and safe when used as directed, both for treating fungal eye infections and as a food preservative. However, it’s essential to follow medical advice and product labeling instructions to minimize the risk of side effects and ensure its effectiveness. If you experience any concerning side effects, consult a healthcare professional promptly.