UDCA powder

Ursodeoxycholic Acid, whose short name is UDCA, is the 7-beta isomer of goose deoxycholic acid (the primary bile acid in normal bile). It is a white powder; odorless, bitter taste. It is soluble in ethanol, glacial acetic acid and sodium hydroxide test solution, and insoluble in chloroform.

Description

UDCA powder-Lyphar Biotech Co., Ltd

Product name Ursodeoxycholic Acid
Other name UDCA
CAS 83-49-8
EINECS No 201-483-2
MF C24H39O4
Purity 98%+
Appearance White powder

UDCA powder-Lyphar Biotech Co., Ltd

UDCA powder-Lyphar Biotech Co., Ltd

UDCA powder-Lyphar Biotech Co., Ltd

Ursodeoxycholic Acid UDCA promotes the secretion of endogenous bile acids and reduces reabsorption.

  1. Cytoprotective effect: Ursodeoxycholic AcidUDCA conjugate significantly reduced the cytolysis of hepatocytes induced by hydrophobic bile acid and reduced apoptosis induced by toxic bile acid in cultured murine and human hepatocytes.
  2. Membrane stabilization: Ursodeoxycholic AcidUDCA can prevent bile acid-induced changes in mitochondrial membrane permeability, which means it can prevent toxic bile acid-induced damage to the mitochondrial membrane, basement membrane and small bile duct membrane through membrane stabilization.
  3. Antioxidant effect: Ursodeoxycholic AcidUDCA can inhibit the activation of blastocytes induced by toxic bile acids, and increase the level of glutathione and thiol-containing protein in hepatocytes to prevent the oxidative damage of hepatocytes.
  4. Immunomodulatory effects: Ursodeoxycholic AcidUDCA inhibits indirectly by reducing the stimulatory impact of hydrophobic bile acids and directly inhibits the expression of histocompatibility complex (MHC) class I and class II genes by activating glucocorticoid receptors.
  5. Ursodeoxycholic AcidUDCA could reduce SARS-Cov-2 entry into cells, which means it can be anti-Covid-19 to some extent, as reported by NATURE recently.

UDCA powder-Lyphar Biotech Co., Ltd

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UDCA powder-Lyphar Biotech Co., Ltd

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