Pterostilbene is a chemical component found in plants, such as blueberries, bilberry fruit, cranberries, lingonberries, huckleberries, and red grapes, It was first discovered in 1977, appearance is a white powder, which has many functions such as antioxidant, anti-cell proliferation, blood lipid-lowering, anticancer, antifungal and so on. For years, it has been one of the most popular supplements in the world.
What is pterostilbene good for?
1. Antioxidant effect
like vitamin C and vitamin E, pterostilbene has been proven to help reduce free radical damage. In the published studies, pterostilbene has been found to show direct antioxidant effects, and also regulate antioxidant enzymes and defense systems in the whole body. It is speculated that many potential health benefits of pterostilbene are related to its antioxidant effect.
2. Balance blood sugar
Pterostilbene has great prospects in helping to control blood sugar and complications of diabetes mellitus. As with many of the other potential benefits of pterostilbene, animal data strongly indicate that pterostilbene has benefits for glucometabolism, and pterostilbene is beneficial to the cardiovascular system, which can delay the aging of vascular endothelial cells and mitochondrial oxidative stress.
3. Brain protection
In a study, pterostilbene can help prevent memory loss and optimize inflammatory reactions and other signs of dementia pathology.
4. Benefits to heart health
Studies have found that pterostilbene also helps protect the heart from damage or optimize cardiac function.
Where to buy Pterostilbene?
Though many plants can found Pterostilbene, but the content is very low and the price is extremely high, so most Pterostilbene in the market is synthetic, we can supply 99% Synthetic Pterostilbene, if you want to know more details, please click Lyphar.
Pterostilbene versus resveratrol
Pterostilbene is similar to resveratrol in structure, and both have antioxidant, anti-inflammatory and anti-cancer properties.
Resveratrol circulates in the body for a short period of time, and its half-life is only 14 minutes, which means that only 14 minutes later, half of the resveratrol will be cleared by the human body. However, pterostilbene stays in the body much longer. This is because compared with the three hydroxyl groups of resveratrol, pterostilbene contains only one hydroxyl group. Hydroxyl makes it easier for the human body to get rid of molecules. Therefore, pterostilbene is more easily absorbed by the intestine than resveratrol. The bioavailability of pterostilbene is about 80% compared to 20% of resveratrol.
In general, pterostilbene has increased lipophilicity, oral absorption, stronger cellular absorption capacity, higher bioavailability and is more stable than resveratrol. pterostilbene is considered as “the next generation of resveratrol”. It has greater potential in clinical application.
Is Pterostilbene safe?
Pterostilbene is considered safe, with no adverse reactions reported at dose up to 500 mg per day. However, some people may experience an increase in LDL cholesterol while using it. Since this compound is commonly found in foods, dietary levels of pterostilbene should be safe.
How much Pterostilbene should I take?
If you want to take Pterostilbene in supplement form, the recommended dosage depends on your body weight and the reason for using it. Unless your doctor advises taking a different dosage, it is usually recommended that you take it based on your body weight.
If you’re under or about 150 pounds, take 200–400 milligrams per day.
If you’re about 200 pounds, take 250–500 milligrams per day.
If you’re over 250 pounds, take between 350–650 milligrams daily.
Pterostilbene can exert anti-tumor effects by inducing tumor cell apoptosis, inhibiting tumor proliferation, invasion and metastasis, inhibiting angiogenesis and tumor stem cell activity. It is worth noting that in the process of inducing tumor cell apoptosis, pterostilbene-induced autophagy can play two different roles: promoting and resisting apoptosis. However, its molecular mechanism has not been elucidated, and further research is needed. Pterostilbene has a significant anti-inflammatory effect, which can inhibit the inflammatory damage of skin, pancreas, colon and other organs and tissues, and inflammation plays an important role in promoting tumor progression. There is no report at home and abroad, and it is worthy of further study. In addition, the presence of tumor stem cells can initiate and maintain tumor growth. At the same time, pterostilbene can reduce the formation of tumor stem cells and inhibit their tumor and stem cell properties, providing clues for new development of therapeutic agents and future drugs for tumor treatment. In addition, studies have found that pterostilbene can inhibit the catalytic activity of cytochrome P450 CYP1A1 and CYP1B1 and scavenge peroxy free radicals, thereby protecting normal cells against carcinogens. Therefore, in addition to anti-tumor effects, pterostilbene also has the ability to prevent cancer. effect. Although most of the currently available data suggest that pterostilbene is pharmacologically active and has no significant toxic effects, more rigorous clinical trials are needed to link in vitro findings with in vivo bioavailability before standardizing dietary or therapeutic doses of pterostilbene into different therapy. Therefore, the anti-tumor mechanism of pterostilbene and its biological safety still need to be further studied.
This paragraph is excerpted from the article on the research progress of the anti-tumor mechanism of pterostilbene, which elaborates the role of pterostilbene and its benefits to human health. For more details about the product, please contact Lyphar, and we have very professional salespeople to answer your questions and your concerns.