Biotinoyl Tripeptide-1 is a cosmetic ingredient widely used in hair and lash care formulations. Here’s a clear, structured overview of its basic information:
1. What It Is
- INCI Name: Biotinoyl Tripeptide-1
- Type: Peptide–vitamin conjugate
- Composition: A combination of biotin (vitamin B7) linked to a short tripeptide (three amino acids)
This hybrid design allows it to deliver both biological signaling (from the peptide) and nutritional support (from biotin).
2. Mechanism of Action
Biotinoyl Tripeptide-1 works through multiple pathways:
(1)Hair anchoring support:
- Strengthens the connection between hair follicles and the scalp by stimulating proteins involved in adhesion.
(2)Keratin production stimulation:
- Promotes synthesis of keratin, the main structural protein in hair.
(3)Microcirculation improvement:
- Helps enhance blood flow around hair follicles, supporting nutrient delivery.
(4)Anti-hair loss signaling:
- May reduce premature hair shedding by prolonging the hair growth phase (anagen phase).

3. Applications of Biotinoyl Tripeptide-1
- Hair growth serums
- Anti-hair loss treatments
- Eyelash and eyebrow enhancers
- Strengthening shampoos and conditioners
4. Benefits of Biotinoyl Tripeptide-1
- Helps reduce hair shedding
- Improves hair strength and thickness
- Enhances follicle vitality
- Supports healthier, fuller-looking lashes and brows
5. Related Complex
Often used as part of Procapil, which also includes:
- Oleanolic acid
- Apigenin
This combination targets hair loss from multiple angles (hormonal, vascular, and structural).
6. Safety & Stability
- Safety: Generally considered safe for topical use in cosmetics
- Irritation risk: Very low
- Stability: Stable in aqueous formulations; works best in leave-on products

7. Typical Use Levels
- Commonly used at 0.5%–2% in formulations (depending on product type)
8. Summary
Biotinoyl Tripeptide-1 is a multifunctional hair-care peptide that combines vitamin support with peptide signaling to:
- Strengthen hair anchorage
- Promote growth
- Reduce hair loss
If you want, I can compare it with other peptides like SNAP-8 or Redensyl, or explain whether it actually works based on clinical evidence.
