Ivermectin is a semisynthetic, anthelmintic agent for oral administration. Ivermectin is derived from the avermectins, a class of highly active broad-spectrum anti-parasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin is a mixture containing at least 90% 5-O-demethyl-22, 23-dihydroavermectin A1a and less than 10 % 5-O-demethyl-25-de(1-methylpropyl)-22, 23-dihydro-25-(1-methylethyl) avermectin A1b, generally referred to as 22, 23-dihydroavermectin B1a and B1b or H2B1a and H2B1b, respectively. The respective empirical formulas are C48H74O14 and C47H72O14, with molecular weights of 875.10 and 861.07, respectively.
Ivermectin for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae effectively, but for adult worms; For only in intestinal fecal round worms are also effective.
Ivermectin powder is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum drug resistant parasites.
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